pH AND ATRACURIUM

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Atracurium and intraocular pressure.

The effect of atracurium on intraocular pressure was studied by comparing it with pancuronium in a randomised controlled trial. The intraocular pressure was measured in patients undergoing cataract surgery before administration of the muscle relaxant, at 1, 3, and 5 minutes after its administration, and at 1 minute after tracheal intubation. Atracurium was found to decrease intraocular pressure...

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Atracurium in infants and children.

For atracurium, as for other neuromuscular blocking agents, the determination of potency in children has been assessed using the evoked response of the adductor muscle of the thumb. This response has been evaluated either by an electromyogram (EMG) or by a recording of the force of contraction through a force displacement transducer. The method of stimulation was either the train-of-four (2 Hz,...

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Anesthesiologist suicide with atracurium.

Atracurium is a nondepolarizing skeletal muscle relaxant used to facilitate endotracheal intubation and to induce skeletal muscle relaxation during surgery or mechanical ventilation. The drug undergoes a spontaneous non-enzymatic biotransformation, yielding laudanosine and an acrylate moiety. This report documents the case of a 45-year-old anesthesiologist who was found dead at the hospital whe...

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Atracurium in anaesthetized man.

Bortoluzzi, E., Roella, C , Bortoluzzi, S. L., and Montoli, E. (1963). Methylphenidate in the treatment of shivering. Anesth. Analg. (Clcvc), 42, 325. Brichard, G., and Johnstone, M. (1970). The effect of methylphenidate (Ritalin) on post-halothane muscle spasticity. Br. J. Anaesth., 42, 718. Maxwell, R. A., Sylwestrowicz, H. D., Holland, R., Schneider, F., and Daniel, A. I. (1961). Some action...

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Pharmacokinetics of atracurium.

Sir,—We congratulate Drs Beetner, Bjorksten and Crankshaw on their description of the pharmacokinetics of atracurium [1]. As they observe correctly, the derivation of pharmacokinetic parameters after a single bolus dose is subject to difficulties because of the presumed degradation of atracurium in sites peripheral to the plasma. In our view, however, the crucial flaw in previous attempts to de...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 1985

ISSN: 0007-0912

DOI: 10.1093/bja/57.5.545